N 510 Module 1: Alterations in Cellular and Immune Functions Assignment
N 510 Module 1: Alterations in Cellular and Immune Functions Assignment
N 510 Module 1: Alterations in Cellular and Immune Functions Assignment: Genetics is Relevant Now Certification:
Register for and complete the Genetics is Relevant Now module at https://research.cchmc.org/gepnlect/cgpn_loginlectora?CourseID=107. Upload the certificate of completion to the dropbox.
Exercises:
Describe the mechanisms that confine cells and tissues to a specific anatomic site.
Discuss the use of tumor markers in cancer diagnoses. Which types of cancer can be diagnosed in this manner? How do tumor markers work? What are the markers actually measuring?
Complete the following table by relating benign and malignant tumors to their sites of origin:
Tissue
Benign Tumor
Malignant Tumor
Connective/mesenchymal tissue
Fibroma
Chondroma
Osteoma
Lipoma
Leiomyoma
Rhabdomyoma
Hemangioma
Hematopoietic
Infectious mononucleosis
Nerve tissue
Neuroma
Neurilemmoma
Epithelial tissue
Papilloma
Ademoma
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Case Study
Complete Case Study #60 (Down’s syndrome) in the Bruyere textbook.
Professional Development
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Write a essay on your choice of the following topics:
Allergies (choose seasonal, environmental, or food)
Cancer (choose pancreatic, lung, breast, or prostate)
The essay should contain at least two scholarly sources in addition to the textbook. It should cover the following points:
Explain the pathophysiology of the disease
Discuss common clinical manifestations
List differential diagnoses
Determine which lab tests would confirm the diagnosis and expected results
Analyze a current protocol for treatment and discuss how the treatment works from the pathophysiological perspective
This first discussion assignment is intended to help each student set a context for the course, establish expectations and goals for the course, and provide insights to the instructor enabling tailoring of the course to better fit the needs of the students. Replies to discussion questions must be well considered and scholarly.
Every course you take should provide the knowledge and skills useful in the real world. Not every course will directly link to every task that you perform in your life or current employment, but learning how to review data, develop data analysis, critical thinking, and writing skills are all needed to convince someone that you can think critically and solve problems. Your ability to pull together and leverage information, insights, and lessons from a number of disparate disciplines in novel ways could be precisely what is needed to stay ahead of your competition and give you a competitive edge.
Your first task is to learn about the course and discover how the skills provided in this course are relevant to you. You will prepare for, post, and engage in a discussion with your classmates and your professor.
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N 510 Module 1: Alterations in Cellular and Immune Functions Assignment
Genetics: Mechanisms that confine cells and tissues to a specific anatomic site
Huether and McCance (2015) opine that cells are in a network of extracellular macromolecules that are called the extracellular matrix. The matric helps in holding the cells as well as the tissues together. The extracellular matrix as well helps in the provision as well as the organization of frameworks that allow for the interaction of cells. For confinement and hence leading to the formation of a tissue, the cells have to be made upon intracellular recognition, is has to have adhesion and it has to have memory. The communication of cells will allow for the production of new cells at the time of need only.
The adhesion molecules differ from one cell type to the other in the plasma membrane that is stuck in the cells of the same kind. The membrane can as well be seen to be stuck on the extracellular matrix components. The cells are made up of a memory because signals are evoked by the specific development of the embryo. The preservation of the autonomy and the different features of the cells are kept due to the fact that the cells are made up of a memory that is passed to the progeny.
N 510 Module 1: Alterations in Cellular and Immune Functions Assignment Rubric
Criteria
Does Not Meet 0%
Approaches 70%
Meets 80%
Exceeds 100%
Content Weight: 30%
0 points
Topic is inappropriate to assignment, inaccurate understanding of concepts, unclear and difficult to understand; does not address many assignment requirements. Information has weak or no connection to the assignment topic.
21 points
Topic is mostly covered and appropriate to assignment, but does not adequately demonstrate accurate understanding of concepts; mostly clear and understandable; lacks some of the requirements of the assignment description and/or provides little detail; Information relates to the main topic, but few details and/or examples are given.
24 points
Topic is covered completely and appropriate to assignment; overview of key concept dimensions is evident; clear and understandable; addresses all of the requirements of the assignment description, with adequate attention to detail.
30 points
In-depth coverage of topic; outstanding clarity and explanation of concepts demonstrated in information presented; approaches assignment with depth and breadth, without redundancy, using clear and focused details.
24 / 30
Organization Weight: 25%
0 points
Organization is confusing and interferes with reader’s ability to follow ideas. Weak or no introduction of topic or purpose is unclear, weak, or missing. Conclusion lacks a summary of topic, or is missing or irrelevant.
17.5 points
Ideas are sometimes disorganized or irrelevant; Flow is sometimes choppy; somewhat clear organization. Basic introduction that states topic but is presented in an uninteresting way. Conclusion contains basic summary of topic without final concluding ideas, may inappropriately introduces new information.
20 points
Structures ideas in a coherent, organized order that has good flow and an obvious framework. Proficient introduction that is interesting and states topic. Conclusion contains good summary of topic with credible concluding ideas and introduces no new information.
25 points
Exceptionally clear, logical, mature, and thorough organization permitting smooth flow of ideas; Introduction that grabs interest of reader and states topic in clear, unambiguous terms. Excellent concluding summary with succinct and precise ideas that impact reader.
25 / 25
Logic/Argument Weight: 15%
0 points
Demonstrates little logical reasoning for the claims and thoughts within assignment; Many claims are weak or illogical.
10.5 points
Lacks some logical reasoning for the claims and thoughts within the assignment; Some claims are weak.
12 points
Uses solid logical reasoning for the claims and thoughts within the assignment.
15 points
Provides exemplary logical reasoning for the claims and thoughts within the assignment.
15 / 15
Support Weight: 20%
0 points
Lacks support; Uses poor sources for references; Citations lack credibility, relevance, or academic quality or are not current; Does not meet the minimum number of required citations in assignment description. APA format and style are not evident.
14 points
Provides weak support or not enough support; Citations are not consistently credible, current, relevant or academic; Meets the minimum number of required citations in assignment description Missing APA elements; in-text citations, where necessary, are used but formatted inaccurately and not referenced.
16 points
Provides sufficient support with credible, current, relevant academic citations; Meets the minimum number of required citations in assignment description. ; In-text citations and a reference page are present with few format errors. Mechanics of writing are reflective of APA style.
20 points
Provides very strong support from credible, current, relevant, academic citations; Meets or exceeds the minimum number of required citations in assignment description. Accurate citations and references are presented. No APA errors are evident.
20 / 20
Quality of Written Communication Weight: 10%
0 points
Style and voice inappropriate or do not address given audience, purpose, etc. Word choice is excessively redundant, clichéd, and unspecific. Inconsistent grammar, spelling, punctuation, and paragraphing. Surface errors are pervasive enough that they impede communication of meaning.
7 points
Style and voice are somewhat appropriate to given audience and purpose. Word choice is often unspecific, generic, redundant, and clichéd. Repetitive mechanical errors distract the reader. Inconsistencies in language, sentence structure, and/or word choice are present.
8 points
Style and voice are appropriate to the given audience and purpose. Word choice is specific and purposeful, and somewhat varied throughout. Minimal mechanical or typographical errors are present, but are not overly distracting to the reader. Correct sentence structure and audience-appropriate language are used.
10 points
Style and voice are not only appropriate to the given audience and purpose, but also show originality and creativity. Word choice is specific, purposeful, dynamic and varied. Free of mechanical and typographical errors. A variety of sentence structures and effective figures of speech are used. Writer is clearly in command of standard, written, academic English.
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